The NIH Mentored Patient-Oriented Research Career Development Award (K23) aims to support clinicians in their career development as researchers focused on patient-oriented research (POR). This opportunity is designed for candidates with a clinical doctoral degree who have committed to research that involves direct interaction with human subjects but excludes leading an independent clinical trial. However, participation in a clinical trial led by a mentor or co-mentor is allowed. This program supports up to five years of salary and research costs to provide a protected time period for these researchers to acquire the necessary skills to transition to independent investigators.

The FOA PA-24-185, which reissues PA-20-205, encourages applications that align with the missions of the participating NIH Institutes and Centers (ICs). Successful candidates will demonstrate strong potential for becoming independent investigators and have the support of a mentor or a mentoring team with proven experience in guiding similar candidates. The research proposed should be aligned with the candidate’s long-term goals in patient-oriented research. In addition, NIH emphasizes the need for inclusive research environments and encourages diversity among applicants.

Applications are due annually on standard NIH deadlines, beginning June 12, 2024. The program is open to higher education institutions, government organizations, nonprofits, and certain for-profit organizations. Candidates must commit 75% of their full-time effort to the career development program. Awards cover salary and other costs related to career development, such as research supplies, equipment, and travel. Mentorship, institutional support, and the proposed research plan are critical elements evaluated during the review process.