The Modeling Infectious Diseases in Healthcare (MInD Healthcare) to Improve Pathogen Prevention and Healthcare Delivery grant is offered by the Centers for Disease Control and Prevention (CDC), National Center for Emerging and Zoonotic Infectious Diseases, Division of Healthcare Quality Promotion. This funding opportunity aims to advance applied mathematical and computational modeling techniques for understanding and predicting the spread of antimicrobial-resistant pathogens in healthcare settings. The goal is to develop predictive models that enhance prevention strategies, optimize intervention effectiveness, and provide public health decision-makers with actionable insights. The program also emphasizes workforce development by training early-career professionals in public health modeling.

The funding opportunity supports research in modeling healthcare-associated infections (HAIs) and antimicrobial-resistant organisms (AROs) to predict outbreaks, assess intervention effectiveness, and analyze pathogen transmission. The MInD Healthcare Network will function as a collaborative system of researchers and public health officials who will conduct modeling studies and generate real-time computational tools. The program also focuses on integrating epidemiological, genomic, and economic data to improve infection prevention strategies across diverse healthcare settings.

The total funding available ranges from $16.5 million to $19.5 million over five years, with an annual funding pool between $3.3 million and $3.9 million. Individual awards will range from $550,000 to $650,000 per budget period, and between four and six awards are expected to be granted. This cooperative agreement will last for five years, with continued funding contingent upon availability and program priorities. There is no cost-sharing or matching fund requirement for this grant.

Eligible applicants include state, county, city, and township governments; special district governments; public and state-controlled institutions of higher education; Native American tribal governments and organizations; 501(c)(3) nonprofits; and private institutions of higher education. Applications exceeding the maximum funding request will be deemed non-responsive. The CDC strongly encourages applicants to collaborate with regional healthcare institutions, public health agencies, and academic entities to enhance the effectiveness of modeling efforts.

Applications must be submitted electronically via Grants.gov and adhere to specific formatting guidelines. The application deadline is April 18, 2025, at 11:59 PM Eastern Time, and an optional letter of intent is due by February 28, 2025. The expected award date is August 16, 2025, with funded projects beginning on September 1, 2025. The CDC emphasizes the importance of early registration with SAM.gov and Grants.gov to avoid submission delays.

The evaluation process consists of a merit review based on criteria such as modeling approach, organizational capacity, proposed collaborations, and workforce development plans. Reviewers will assess the feasibility, innovation, and impact of proposed modeling studies. Special consideration may be given to projects that address high-priority antimicrobial-resistant pathogens and underrepresented populations affected by HAIs. Successful applicants will be required to submit annual progress reports, financial statements, and final performance reports to CDC.

For inquiries, applicants can contact Nga Vuong (ypg2@cdc.gov, 970-494-6682) for program-related questions and Kathy Raible (kcr8@cdc.gov, 470-316-8061) for grants management assistance.