The purpose of this Notice of Funding Opportunity (NOFO) is to advance efforts for a nationally integrated animal food safety system providing State animal food regulatory programs the ability to achieve and maintain full implementation of the Animal Feed Regulatory Program Standards (AFRPS), and to fund optional projects for State animal food regulatory programs to develop and standardize processes, procedures, systems, and other methods to integrate federal and state animal food regulatory work resulting in mutual reliance.Specific outcomes may include, but are not limited to: State animal food regulatory programs will achieve and maintain implementation of the AFRPS, which is recognized as a critical element to creating a national, fully integrated food safety system. Operational use of standardized animal food regulatory systems developed by state programs to compel federal reliance on state regulatory work and resources and reciprocal state reliance on federal work and resources, resulting in mutual reliance.Outputs, Objectives, and Outcomes for this NOFO are currently under development and subject to change before the submission of the NOFO for clearance.