The BJA FY25 Comprehensive Opioid, Stimulant, and Substance Use Site-Based Program (COSSUP) offers funding to support government efforts in addressing the impact of illicit substance use on individuals and communities. The program emphasizes reducing overdose deaths, increasing access to treatment and recovery services, and enhancing public safety and community resilience. It encourages multi-disciplinary approaches that integrate public health, behavioral health, and criminal justice systems.

The program provides a total of $104,400,000 in funding, with three categories of awards: local governments (up to $1,600,000), state governments (up to $7,000,000), and tribal governments (up to $1,000,000). Projects may include harm reduction activities, law enforcement-led diversion programs, substance use treatment expansion, recovery support services, and public awareness initiatives. Funding will be distributed across urban, suburban, and rural areas, with up to 49 awards anticipated.

Eligibility extends to state, local, and tribal governments, as well as agencies and entities working within these systems. Applicants must demonstrate a focus on areas with significant overdose increases or underserved populations. Partnerships with community organizations, law enforcement, and treatment providers are encouraged. The program prioritizes geographic diversity, equitable access, and the inclusion of research and evaluation components.

Applications involve a two-step submission process via Grants.gov (SF-424) and JustGrants. Required components include a proposal narrative, a budget detail form, and performance measurement plans. Deadlines are March 12, 2025, for Grants.gov and March 19, 2025, for JustGrants. Pre-application webinars and technical assistance resources are available to aid applicants.

Evaluation criteria include alignment with program goals, innovation, feasibility, organizational capacity, and budget justification. Applications will undergo merit review, financial review, and risk assessment. Awardees will be notified by September 30, 2025, and must adhere to federal reporting and compliance requirements, including quarterly performance and financial reports.

Award recipients are expected to deliver comprehensive, evidence-based interventions targeting substance use and its impacts. Projects must integrate stakeholder collaboration, data-driven strategies, and public health approaches. Post-award support includes access to technical assistance and capacity-building resources. For detailed guidance, applicants are advised to consult the NOFO and accompanying resource guides.