The Promoting Results and Outcomes through Policy and Economic Levers (PROPEL) Annual Program Statement (APS) by USAID, referenced as 7200AA22APS00002, aims to improve health outcomes in areas such as family planning and reproductive health (FP/RH), maternal and child health (MCH), and HIV/AIDS. The program emphasizes enhancing the enabling environment for equitable and sustainable health services, focusing on policy development, financing, governance, and advocacy. Through PROPEL, USAID seeks to strengthen health systems by fostering policies that support sustainable financing, transparency, government stewardship, and civil society engagement. This initiative targets better integration of FP/RH with other health sectors like MCH and HIV/AIDS, promoting cross-sectoral approaches to achieve comprehensive health improvements.

The APS functions as an umbrella mechanism that invites submissions through specific "Rounds" over time, each addressing particular health priorities or geographic areas. Each Round provides unique funding opportunities that align with the overarching goal of PROPEL but may include distinct eligibility criteria, geographic focuses, or programmatic themes. The APS is open until November 30, 2027, with multiple awards expected from various Rounds based on available funding. The period of performance for awarded projects will not exceed five years, with specific requirements and guidelines detailed in each Round document.

Eligible applicants include U.S. and international public, private, for-profit, and nonprofit organizations, academic institutions, and non-governmental entities. There is an emphasis on engaging local partners, particularly in developing countries, to build capacity and ensure sustainable development. Cost-sharing is generally required, with the specifics outlined in individual Rounds. The APS encourages new partners to participate, aiming to expand USAID’s partnership base through initiatives that incorporate local organizations and private sector actors in project implementation.

Submissions follow a multi-step process, starting with a concept paper submission. Selected applicants may then engage in a co-creation process with USAID to refine project designs before submitting full proposals. USAID’s involvement may include approving implementation plans, collaborating on monitoring and evaluation activities, and ensuring alignment with the program's goals. The agency retains the right to approve key personnel and may exercise substantial involvement in certain aspects of project execution.

The APS also incorporates environmental considerations, adherence to USAID's regulations, and substantial involvement by USAID in project oversight. Awards aim to promote sustainable health policies, increase financial resource optimization, support evidence-based advocacy, and integrate FP/RH with broader development initiatives. The program aligns with USAID’s commitment to achieving the Sustainable Development Goals and improving health outcomes globally, particularly in regions with high health needs.