Quagga and Zebra Mussels are aquatic invasive species that are rapidly expanding their range in the Western United States. Popular recreational reservoirs on or connected to the lower Colorado River are one major source of invasive mussels, which are easily transported via trailered watercraft to areas that have not yet been invaded. This Request For Proposals (RFP) will fund proposals in the listed principal areas towards the fulfillment of the top priorities in the Quagga/Zebra Mussel Action Plan for Western U.S. Waters (QZAP 2.0) and will be limited to states within the boundaries of the Western Regional Panel within the United States, not including Canada and Mexico (see map): Limiting the spread of invasive mussels through containment, especially by inspection and decontamination of watercraft moving from invaded water bodies to jurisdictions currently free of dreissenid mussels, and the coordination between states or other jurisdictions to this end;1. Protecting western ecosystems through support and/or establishment of prevention programs for invasive mussels at identified high risk control points. 2. Limiting the spread of invasive mussels through containment by increasing compliance with federal, state, local and tribal laws; 3. Increasing the effectiveness of outreach and education efforts to help advance prevention efforts; 4. Building capacity to detect and respond to new invasive mussel infestations;5. Conducting Research that benefits the priorities listed above, including (but not limited to) social science research to evaluate the effectiveness of invasive species prevention messaging, and research on non- target species impacts of invasive mussel control treatments (See Research Priorities: https://www.reabic.net/journals/mbi/2023/Accepted/MBI_2023_Counihan_et al_correctedproof.pdf) Efforts to address the risks and impacts of these invasive species are on-going. They include development of QZAP, and funding by the U.S. Fish Wildlife Service (Service) to address waters at highest risk for spreading invasive mussels. In fiscal year 2024 the Service plans to allocate approximately $2,200,000 to projects that will reduce or minimize the threat of quagga and zebra mussels to Western U.S. waters. Funding is available for a limited number of projects that target the priories listed above.