The United States Government, represented by the United States Agency for International Development (USAID) at its Mission in Southern Africa through the Bilateral Health Office (BHO) is publishing this Request for Information to obtain information and input from all interested entities, U.S. and non-U.S. organizations, on a potential future HIV Prevention among Adolescent Girls and Young Women and Other Vulnerable Youth Populations (North) Activity (also referred to as DREAMS North) and or HIV Prevention among Adolescent Girls and Young Women and Other Vulnerable Youth Populations (South) Activity (also referred to as DREAMS South). The information will be used to help make planning decisions and may inform activity design to improve future development outcomes. This Request for Information (RFI) is issued solely for information gathering purposes and is published inaccordance with FAR Part 10 and FAR 15.201(e).