The Centers of Research Excellence in Science and Technology (CREST) program provides support to enhance the research capabilities of minority-serving institutions (MSIs) through the establishment of centers that effectively integrate education and research. CREST promotes the development of new knowledge, enhancements of the research productivity of individual faculty, and an expanded presence of students who are members of groups underrepresented in science, technology, engineering, and mathematics (STEM) disciplines. The CREST Postdoctoral Research Program (CREST-PRP) awards are part of the overarching CREST program and provide two years of support for research experience and training for early career scientists at active CREST Centers. The goal of the CREST-PRP awards isto increase the workforce presence of individuals from groups underrepresented in STEM fields. CREST-PRP awards recognize investigators with significant potential and provide them with research experiences that broaden perspectives, facilitate interdisciplinary interactions, and prepare CREST-PRP scholars for positions of leadership within the scientific community. Postdoctoral scholars conduct research on topics aligned with the research focus of the host CREST Center. The awards are also designed to provide active mentoring to the postdoctoral scholars by thescientific mentorwho, in turn, will benefit from the incorporation of these talented scientists into their research groups. Proposals must be submitted by individual postdoctoral candidates. However, if an award is recommended, the award will be transferred to the host institution where the postdoctoral scholar will be named as the PI. The award will be issued to the host institution as a regular research award, and the award will be administered by the host institution. Women, veterans, persons with disabilities, and members of groups underrepresented in STEM are especially encouraged to apply.