The National Science Foundation, in partnership with the Center for the Advancement of Science in Space, Inc. (CASIS), has announced the NSF/CASIS Transport Phenomena Research at the International Space Station to Benefit Life on Earth funding opportunity. This initiative supports research utilizing the unique environment of the International Space Station (ISS) National Lab to address scientific and engineering challenges in fluid dynamics, particulate and multiphase processes, combustion and fire systems, thermal transport processes, nanoscale interactions, and manufacturing methods involving these phenomena. Additionally, research outcomes are expected to lead to advances in metallic materials, metal nanostructures, and ceramic materials with tangible benefits for life on Earth.

The funding opportunity is open to U.S.-based for-profit organizations, including small businesses with strong scientific and engineering research capabilities, and non-profit, non-academic organizations such as museums, observatories, and research laboratories. Accredited institutions of higher education, including two- and four-year colleges and universities located in the United States, are also eligible to apply. If proposals involve international branch campuses of U.S. institutions, applicants must justify the necessity of performing project activities at the international site rather than the U.S.-based campus. Principal Investigators (PIs) and Co-PIs must meet the legal definition of "U.S. Persons" under 22 U.S. Code §6010, which includes U.S. citizens, permanent residents, and U.S.-based organizations.

The program seeks to leverage the microgravity and controlled conditions available on the ISS to explore phenomena that are difficult or impossible to study on Earth. Research areas may include investigating fluid behavior in low-gravity environments, developing novel thermal management systems, improving nanoscale manufacturing methods, and exploring material properties under space conditions. The results are expected to yield innovations with broad implications for industries such as aerospace, manufacturing, materials science, and environmental engineering.

The estimated total funding available for this opportunity is $3,600,000. While there are no predefined award ceilings or floors, the number of awards will depend on the quality of submissions and available funding. Cost sharing or matching funds are not required for eligibility. Applications must be submitted by April 10, 2025, and no late submissions will be accepted.

Proposals should clearly articulate the significance of the research, its potential societal and economic impact, and the necessity of conducting experiments aboard the ISS. Applicants are encouraged to address how their proposed research will advance scientific understanding, contribute to technological development, and benefit broader communities. The evaluation process will consider the intellectual merit, broader impacts, feasibility, and alignment with program objectives.

For further information, applicants can refer to NSF Publication 25-529 or contact NSF Grants.gov support via email at grantsgovsupport@nsf.gov. The application materials and additional guidelines are available on the official NSF and Grants.gov websites.