The NIH Mentored Patient-Oriented Research Career Development Award (K23), funding opportunity number PA-24-186, supports the career development of clinicians with a focus on patient-oriented research. The program is intended for researchers with a clinical doctoral degree and involves basic experimental studies with humans that meet the NIH’s definition of both clinical trials and basic research. These studies aim to increase understanding of fundamental aspects of human phenomena without direct applications toward clinical outcomes or products. The K23 award provides salary and research support for 3-5 years to foster the career progression of scientists committed to patient-oriented research.

Applicants must propose basic science experimental studies that involve prospectively assigning human participants to different conditions to assess biomedical or behavioral outcomes. The award requires a detailed career development plan and mentorship from an experienced investigator. The NIH encourages the inclusion of diverse perspectives and advises candidates to review the program-specific requirements of participating NIH Institutes and Centers (ICs).

Eligible applicants include U.S.-based higher education institutions, nonprofits, for-profit organizations, and government agencies. Candidates must devote at least 75% of their professional effort to this program. Applications are due starting June 12, 2024, with multiple submission deadlines through 2027. The application process includes registration through the NIH eRA Commons, and detailed guidance is provided in the application guide.