The Alcohol Health Services Research (R34 Clinical Trial Optional) funding opportunity, issued by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), supports research to address gaps in treatment for alcohol use disorder (AUD). This program focuses on improving access, appeal, cost structures, dissemination of evidence-based treatments, and reducing health disparities among populations affected by AUD.

Applicants can propose pilot research projects or small-scale studies to test innovative approaches to improve alcohol health services. This includes interventions aimed at increasing treatment access, enhancing the appeal of existing therapies, evaluating financial and insurance models, studying the implementation of evidence-based practices, and addressing disparities in AUD treatment among underrepresented or health disparity populations.

Eligible applicants include state and local governments, public and private institutions of higher education, nonprofits, for-profit organizations, tribal governments and organizations, small businesses, and community-based organizations. Minority-serving institutions, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions (HSIs), and Tribally Controlled Colleges and Universities (TCCUs), are also encouraged to apply. International applicants may participate under specific guidelines.

This funding opportunity provides flexible support for studies with the potential to inform larger-scale interventions. Applications are accepted through September 7, 2026, without specified limits on funding ceilings or floors. Projects can optionally include clinical trials but must focus on generating insights that directly address gaps in AUD treatment and care.

For further details and application requirements, refer to the full NOFO or contact NIH Grants Information at grantsinfo@nih.gov. This opportunity is critical for advancing the understanding and delivery of effective AUD treatments, fostering innovative solutions, and addressing barriers to care for underserved populations.