The purpose of this Notice is to alert the community that NHGRI plans to publish a Funding Opportunity Announcement (FOA) to transform NHGRIs Diversity Action Plan (R25 Clinical Trials Not Allowed) to better align with more recent NHGRI and NIH-wide efforts to increase workforce diversity. Individuals from diverse backgrounds are needed to address research challenges and opportunities in genome sciences, genomic medicine, genomics and society, data science, and health equity research. To build on the remarkable metamorphosis of the field of genomics over the last three decades, enhancing the diversity of the genomics workforce must be embraced as an urgent priority. Toward that end, NHGRI recently developed an action agenda for training, employing, and retaining a genomics workforce that reflects the diversity of the US population. Relevant to its training and career development portfolio, NHGRI is committed to supporting pathways that help diverse groups of individuals develop the skills and knowledge to pursue a career in genomics. Recent strategic planning undertaken at NHGRI underscores this commitment, as described in the 2020 NHGRI Strategic Vision, the NHGRI Action Agenda for Building a Diverse Genomic Research Workforce, and the NHGRI Training Task Force Report presented to the National Advisory Council for Human Genome Research in February, 2020.