The U.S. Army Medical Research Acquisition Activity (USAMRAA) is soliciting applications to
the fiscal year 2024 (FY24) Epilepsy Research Program (ERP) using delegated authority
provided by United States Code, Title 10, Section 4001 (10 USC 4001). The Congressionally
Directed Medical Research Programs (CDMRP) at the U.S. Army Medical Research and
Development Command (USAMRDC) is the program management agent for this funding
opportunity. Congress initiated the ERP in 2015 to provide support for longitudinal
epidemiological research to better understand the incidence of post-traumatic epilepsy (PTE)
following a traumatic brain injury (TBI) and to improve patient care and outcomes. The FY24
ERP challenges the research community to (1) investigate topics related to epileptogenesis for
the identification of mechanisms by which brain injury produces epilepsy, (2) study the
prevention of PTE and concomitant comorbidities, and (3) develop innovative research tools or
biomarkers to better detect, diagnose, or predict the development of PTE. Appropriations for the
ERP from FY15 through FY24 totaled $85.5 million (M). The FY24 appropriation is $12M.
The ERP encourages collaboration among PTE researchers and urges the scientific community to
utilize equitable partnerships with people living with PTE to maximize the translational and
impact potential of proposed research. Applications from investigators within the military
Services and applications involving multidisciplinary collaborations among academia, industry,
the military Services, the U.S. Department of Veterans Affairs (VA), and other federal
government agencies are highly encouraged. These relationships can leverage knowledge,
infrastructure, and access to unique clinical populations that the collaborators bring to the
research effort, ultimately advancing research that is of significance to Service Members,
Veterans, their Families and/or care partners.