The Making America Healthy Again by Addressing Dementia Disparities grant opportunity is a forecasted discretionary funding program from the Office of the Assistant Secretary for Health within the U.S. Department of Health and Human Services. The initiative falls under the authority of 42 U.S.C. § 300u-6, Section 1707 of the Public Health Service Act, and is designed to support demonstration projects aimed at reducing disparities that impact brain health among aging populations, particularly in minority and underserved communities.

The primary objective of this grant is to fund innovative, community-focused, and evidence-based or informed projects that address subjective cognitive decline (SCD) as an early sign of dementia, including Alzheimer’s disease. The program seeks to mitigate the influence of social determinants of health (SDOH) and other environmental risk factors through novel strategies implemented in communities where people live, work, learn, play, and worship. It aligns with the HHS Secretary’s health priorities and the Make America Healthy Again Commission, emphasizing chronic disease prevention and healthy aging. Projects are expected to support the Healthy People 2030 objectives related to dementia.

Eligible applicants include a wide range of public and nonprofit entities based in a U.S. state or territory. These include state and local governments, public housing authorities, Native American tribal governments and organizations, school districts, public and private nonprofit higher education institutions, and nonprofit organizations with or without 501(c)(3) status. Faith-based and community-based organizations are also eligible. However, for-profit organizations and individuals are not eligible. Applicants must ensure their registration with SAM.gov and Grants.gov is active at the time of application submission.

Applications are projected to open on April 14, 2025, with a submission deadline of June 23, 2025, by 6:00 PM Eastern Time. Awards are expected to be announced by September 15, 2025, with project start dates beginning as early as September 30, 2025. A total of $5,000,000 is anticipated for this funding cycle, with nine awards expected. The individual award amounts will range from $450,000 to $600,000. Matching funds are not required. Projects are expected to follow 12-month budget periods and may be eligible for continuation funding contingent on progress and funding availability.

Applications must be submitted electronically through Grants.gov, and early registration in the system is strongly encouraged due to potential administrative delays. Multi-year projects will require a non-competing continuation (NCC) application for subsequent budget periods. Project designs should include consideration for sustainability beyond the grant period. Contact for this grant opportunity is Stacey Williams, who can be reached by phone at 240-453-8444 or via email at OMHGrants@hhs.gov.