The DOE SC program in Biological and Environmental Research (BER) hereby announces its interest in receiving applications for research within the Biological Systems Science Divisions (BSSD) Genomic Science Program (GSP) (http://genomicscience.energy.gov) mission-space. This NOFO solicits applications for Genomics - Enabled Understanding and Advancing Knowledge on Plant Gene Function(s) to effectively design bioenergy crops by developing approaches to: a) understand regulatory elements, biological mechanisms and develop predictive models for dissecting multigene traits and their component parts that govern plant growth under different growing conditions, biochemical and signaling pathways; b) understand genetic components and molecular mechanisms underlying plant regeneration/organogenesis in tissue culture to improve heterologous DNA transfer to germlines of bioenergy crops; and c) understand genetic and molecular mechanisms that will reduce the cycle time for out-crossing energy crops (e.g. self-incompatibility) to speed development of new plant feedstocks underpinning a more broader and more competitive U.S. bioeconomy.