Notice of Intent to Publish a Funding Opportunity Announcement for Complement-ARIE New Approach Methodologies (NAMs) Data Hub and Coordinating Center (U24 Clinical Trial Optional)
This funding opportunity provides $5 million to support the development of a centralized resource for innovative research methods that reduce or replace animal testing in biomedical studies, inviting a wide range of eligible organizations to apply.
Description
The National Institutes of Health (NIH) has issued a Notice of Intent to Publish a Funding Opportunity Announcement (FOA) for the Complement Animal Research In Experimentation (Complement-ARIE) New Approach Methodologies (NAMs) Data Hub and Coordinating Center. This FOA, anticipated for release in late 2024, aims to establish a data hub and coordinating center to support the Complement-ARIE program. The purpose of the program is to advance the use of New Approach Methodologies (NAMs) as alternatives to traditional animal research models, fostering innovative approaches to biomedical research while addressing ethical, scientific, and practical considerations.
The envisioned initiative will be structured as a cooperative agreement under the U24 activity code, which implies significant involvement from NIH program staff in project oversight and execution. The primary objectives of the NAMs Data Hub and Coordinating Center will include centralizing and managing NAM-related data, coordinating research efforts across multiple institutions, facilitating data sharing and standardization, and promoting collaborations across the research community. The center will also be responsible for supporting communication, training, and outreach efforts to ensure effective implementation and widespread adoption of NAMs.
NIH expects to make one award under this funding opportunity, with an estimated total program funding of $5,000,000 and an award ceiling of $5,000,000. The anticipated start date for the funded project is December 1, 2025.
Eligible applicants for this opportunity will include Native American tribal governments, nonprofits with 501(c)(3) status, tribal organizations, county and state governments, small businesses, independent school districts, public housing authorities, private and public institutions of higher education, and other eligible entities as specified in the forthcoming FOA. Cost sharing or matching funds will not be required.
The NIH has issued this notice to provide potential applicants sufficient time to build partnerships, prepare responsive proposals, and strategize effectively ahead of the application period. Interested applicants are encouraged to monitor Grants.gov and the NIH funding opportunities page for the official release of the FOA in late 2024.