The National Institutes of Health (NIH), through the National Library of Medicine (NLM), has issued the reannouncement of the “NLM Information Resource Grants to Reduce Health Disparities and Promote Health for All (G08 Clinical Trial Not Allowed)” under Funding Opportunity Number PAR-24-281. This grant opportunity supports projects focused on improving health information resources that can reduce health disparities among vulnerable populations and promote overall health. Applicants are encouraged to reread the announcement carefully as of the March 31, 2025 update to ensure their proposals align with updated agency priorities.

This funding opportunity is intended to support resource grant applications that deliver accurate, accessible, and understandable health information to populations experiencing health disparities and the healthcare providers that serve them. It emphasizes the use of information technology and medical or health libraries to develop or improve health information resources and services. Proposed projects should address a specific health information problem, provide a sustainable and user-centered solution, and show measurable benefit to the target population. The inclusion of a medical or health library as a collaborator is mandatory for project eligibility.

Funding is available for up to $200,000 per year in direct costs, with a maximum project duration of three years. The program does not support clinical trials and requires a comprehensive resource evaluation and sustainability plan. Specific examples of responsive projects include the development of health information services for community organizations, culturally tailored education on clinical trials, and visual or interactive tools to facilitate health decisions. Proposals that do not target populations with health disparities or lack medical library collaboration are considered non-responsive and will not be reviewed.

Applicants can submit new or resubmission applications, with letters of intent due on November 13, 2024, April 25, 2025, and April 24, 2026. Full application deadlines follow NIH’s standard due dates, with the next major submission due on December 13, 2024. Applications must be submitted via Grants.gov or NIH’s ASSIST system. A detailed application package is available through these portals, and specific formatting and content requirements must be followed, including guidance on resource development strategies, dissemination plans, and letters of support from communities.

Applications are reviewed based on criteria including the significance of the proposed project, qualifications of the investigators, innovation, approach, and overall environment. The review process includes a peer scientific merit review followed by an advisory council review. Evaluation criteria also examine the project’s ability to reach underserved populations, involve relevant stakeholders, and promote sustainability. Final award decisions are contingent on availability of funds and programmatic priorities.

Questions regarding scientific and research aspects should be directed to Dr. Sung Sug (Sarah) Yoon or Dr. Elizabeth Anne Barr, while peer review questions can be addressed to Dr. Zoe Huang. Grants management concerns should be directed to Andrea Culhane. The initiative is authorized under 42 USC 286b-5 and governed by federal regulation 42 CFR Part 59a. Compliance with all federal and NIH-specific regulations and policies is mandatory for applicants and awardees.