The grant opportunity CDC-RFA-JG-25-0176, titled "Protecting and Improving Global Health Security through Local Partner Engagement: Strengthening and Sustaining Public Health Systems in Ghana," is a forecasted funding initiative provided by the Centers for Disease Control-GHC under the Department of Health and Human Services. This program aims to build and maintain a resilient public health system in Ghana capable of preventing, detecting, and responding to public health threats. It emphasizes leveraging multi-sectoral and multilateral partnerships to enhance leadership, capacity, and infrastructure for infectious disease management.

The primary objectives of this funding opportunity are to prevent avoidable epidemics, detect health threats early, and respond effectively to public health emergencies. Activities under this NOFO will build on previous investments, such as laboratory and surveillance improvements, emergency response enhancements, and workforce development efforts initiated under NOFO GH20-2110. Expanded areas of focus include strengthening laboratory and surveillance capacity in border districts, as well as advancing sequencing and bioinformatics capabilities.

This grant is structured as a cooperative agreement with an estimated total program funding of $125,000,000. Two awards are expected to be made, with no cost-sharing or matching requirement. The award ceiling and floor are listed as $0, suggesting further clarification will be provided in the finalized Notice of Funding Opportunity (NOFO). Eligible applicants include a broad range of entities, such as nonprofits (with or without 501(c)(3) status), for-profit organizations, public and private institutions of higher education, small businesses, Native American tribal governments and organizations, public housing authorities, and local, state, and county governments.

The estimated timeline for this opportunity includes a posting date of February 7, 2025, and an application deadline of April 8, 2025, by 11:59 PM ET. Awards are anticipated to be announced on August 29, 2025, with projects set to begin on September 30, 2025. Interested applicants are advised to prepare in advance to meet these deadlines.

Detailed submission requirements and evaluation criteria will be provided in the finalized NOFO. Applications will likely need to demonstrate the applicant’s capacity to implement surveillance and laboratory enhancements, foster international collaboration, and achieve measurable improvements in public health security. The CDC will evaluate proposals based on alignment with the program's objectives and potential impact.

For further details, applicants can contact Shana Eatman at 770-488-3933 or via email at DGHPNOFOs@cdc.gov. Additional updates and related opportunities are available through the Grants.gov platform.