The BMFRP Idea Development Award (IDA) is intended to support innovative ideas and high-impact approaches based on scientifically sound evidence to move toward the BMFRPs vision of understanding and curing BMF diseases. This award mechanism is designed to support new ideas. Proposed research studies should have a high probability of revealing new avenues of investigation. The research project should include a well-formulated, testable hypothesis based on strong scientific rationale and a well-developed and articulated research approach. Hypothesis-driven correlative studies associated with clinical trials that meet the innovative intent of this award mechanism are encouraged. An application that proposes a correlative study should be associated with a clinical trial(s), and the proposed study should facilitate the generation of new hypotheses or advance the understanding of disease biology, treatment mechanisms, or other innovative and impactful outcomes. Funding to conduct the clinical trial itself is outside the scope of this funding opportunity.This funding opportunity is open to Established Investigators (EIs) and Early-Career Investigators (ECIs). ECIs will be assessed using different criteria for personnel during the review process (refer to Section II.E.1.a, Peer Review). Independent of career level, personnel on the proposed team should have a strong background in BMF disease research.