This NOFO aims to conduct diabetes surveillance across health system and/or health plan membership-based centers to: (1) Estimate incidence and prevalence of diabetes in youth (;lt; 18 years) and young adults (1844 years) in the United States. These estimates are sought by diabetes type, demographic traits, health insurance status, and geographic area to identify disparities in diabetes burden; and (2) Ascertain the prevalence of risk factors for diabetes complications, occurrence of acute and chronic diabetes complications, and use of diabetes medications among youth and young adults with diabetes. This NOFO has two (2) components to achieve the purpose of the program. Component A focuses on surveillance of diabetes among youth (;lt; 18 years) and young adults (1844 years). Component B serves as a Coordinating Center to provide an infrastructure for standardized approaches, analytical methods, and measures to be used for surveillance across sites. It will also develop validation protocols, serve as a data repository, and provide statistical expertise.