The overarching goal of the ARC UE5 program is to provide ARC F99 fellows/K00 scholars with professional skills and the appropriate mentoring and networks to allow them to transition into and succeed in postdoctoral research and career development opportunities, positioning them to advance in impactful careers in the biomedical research workforce that typically require postdoctoral training (e.g., academic research and teaching at a range of institution types, industry or government research). To accomplish the stated over-arching goal, this Notice of Funding Opportunity will support evidence-informed educational activities with a primary focus on courses for skills development and mentoring activities.